Synthetic Impuritiesproduct list
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 Acyclovir  BP  Guanine
 (Imp B)

 2-amino-1,7-
 dihydro-6H-
 purin-6-one

 Adapalene  INH    a) Brom-
 onapthoic acid
 Adapalene  INH    b) methyl-
 6-bromo-2-
 naphthoate
 Adapalene  INH    c) 2-(1-adam-
 antyl)-anisole
 Adapalene  INH    d) Anisole-2-
 (1-adamantyl)
 -4-bromo
 Adapalene  INH    e) methylester
 of adapelene
 Adapalene  INH    f) 3,3-diada-
 mantyl- 4,4’ -
 dimethoxy
 biphenyl
 Alprazolam  INH  Triaz- 
 olam
 
 Amlodipine
 Besilate
 BP  Amlod-
 ipine
 Imp D
 3-ethyl-5-ethyl
 -2-[(2-amino-
 ethoxymethyl]
 -4-(2-chloro-
 phenyl)-6-
 meth-ylpyridine
 -3,5-dicarbo-
 xylate
 Amlodipine
 Mesylate
 BP  Amlod-
 ipine
 Imp D
 3-ethyl
 5-methyl-
 2-[(2-amino- 
 ethoxymethyl]
 -4-(2-chloro-
 phenyl)-6-met-
 hylpyri-dine
 -3,5-dicarb-
 oxylate
 Amoxycillin  BP  a) imp
 D
 a) Sodiumsalt
 of amox-
 icilloic acid
 Amoxycillin  BP  b) imp.
 C
 b) Diketo piper-
 azineamox-
 ycillin
 Ampicillin  BP  a) imp
 D
 a) Sodium salt
 of ampiclloic-
 acid
 Ampicillin  BP  b) imp.
 C
 b) Diketop-
 iperazine of
ampicillin
 Amplodipine
 Maleate
 BP  Amlod-
 ipine
 Imp D
 3-ethyl 5-
 methyl-2-
 [(2-amino-
 ethoxymethyl]
 -4-(2-chlor-
 ophenyl)
 -6-methy-
 lpyridine-
 3,5-dicarb-
 oxylate
 Anagrelide
 HCL
 INH    a) Methyl-5-6-
 dichloro-3,4-
 dihydro 2[1H]
 iminoquin-
 azolin-3-
 acetate
 Anagrelide
 HCL
 INH    b) Ethyl-5,6-
 dichloro3,4-
 dihydro2[1H]
 iminoquin- 
 azolin-3- 
 acetatehydro-
 bromide
 Anagrelide
 HCL
 INH    c) 6,7,8-
 trichloro
 1,5-dihydro
 imidazo
 (2,1-b)
 quinazolin-2
 (3H)-one
 Anagrelide
 HCL
 INH    d) 5,6-dichloro
 3,4-dihydro
 -amino
 quinazolin
 -3-aceticacid
 Anagrelide
 HCL
 INH    e) 5,6-dichloro
 3,4-dihydro
 2[1H]imino
 quinazolin
 Anastrozole  INH    a) a,a,a',a'-
 Tetramethyl- 
 5(1H-1,3,4- 
 triazol-1-yl-
 methyl)-1,3- 
 benzene-diacet- 
 onitrile
 Anastrozole  INH    b) 2,2'-(5- 
 methyl-1,3-
 phenylene)
 -di-(2-methyl
 propiononitrile)
 Anastrozole  INH    c) 3,5-bis
 (cyano-1-
 methylethyl
 benzylbr-
 omide)
 Artemether  INH    a)Dihydro-
 artemisinin
 Artemether  INH    b) Alpha-
Artemether
 (Oil cointa- 
 ining30%
 impurity)
 Artesunate  INH    Dihydro-
artemisinin
 Beclometh-
 asone
 Dipropionate
 BP  a) imp J  a) 9,11b-
 epoxy-16b- 
 methyl-3,20- 
 dioxo-9b-
 regna-1,4-
 diene-17,21-
 diyl
 dipropanoate,
 Beclometh-
 asone
 Dipropionate
 BP b) imp H  b) 9-chloro- 
 11b,21-dihy-
 droxy-16b-
 methyl-3,20-
 dioxopregna-
 1,4-dien-17- 
 yl propanoate
 (beclometa-
 sone 17-propi-
 onate),
 Beclometh-
 asone
 Dipropionate
 BP  c) imp G  c) 9-chloro- 
 11b,17,21-trihy- 
 droxy-16b- 
 methyl-
 pregna-1,4-
 diene-3,20-
 dione(becl-
 ometasone),
 Beclometh-
 asone
 Dipropionate
 BP  d) imp D  d) 9-bromo-
 11b-hydroxy
 -16b-methyl-
 3,20-diox-
 opregna
 -1, 4-diene-
 17,21-diyl-
 dipro-panoate,
 Beclometh-
 asone
 Dipropionate
 BP  e) imp A  e) 9-chloro-
 11b,17-dihy-
 droxy-16b-
 methyl-3,20-
 dioxopregna-
 1, 4-dien-
 21-yl prop-
 anoate (becl-
 ometasone
 21-propionate),
 Beclometh-
 asone
 Dipropionate
 BP  f) imp B  f) 21-(acetyl-
 oxy)-9-chloro-
 11b-hydro-
 xy-16b-methyl-
 3,20-dioxo-
 pregna-1,
 4-dien-17-yl
 propa-noate
 (beclometa-
 sone-21-
 acetate 17-
 propionate),
 Beclometh-
 asone
 Dipropionate
 INH  g)Beclo-
 metha-
 sone
 21-
 butyrate
 g) 9-chloro-
 11b,17-dihydr-
 oxy-16b-methyl-
 3,20-dioxopre-
 gna-1,4-dien-
 21-yl buta-
 noate
 Bicalutamide  INH    a) (±)N-[4-cya-
 no-3(triflu-
 oro-methyl)
 phenyl]-3[(4-flu-
 oro phenyl)
 thio]-2 hyd-
 roxy-2-methyl-
 propanamide
 Bicalutamide  INH    b) (±)N-[2- 
 cyano-3(triflu-
 oromethyl)
 phenyl]-3[(4-
 fluorophenyl)
 sulfinyl]-2-
 hydroxy-2-
 methylpropa-
 namide
 Bicalutamide  INH    c) (±)N-[4- 
 cyano-3(trif-
 luoromethyl)
 phenyl]-3
 [(4-fluoro
 phenyl)sulfinyl]
 -2-hydroxy-2-
 methylpropa-
 namide
 Brimonidine
 Tartarate
 INH    a) 5-Bromo,
 6-amino
 quinaxaline
 Brimonidine
 Tartarate
 INH    b) 6-amino
 quina-xaline
 Budesonide  BP  a) imp D  a) 16a,17-(1RS)-
 butylidenebis
 (oxy)]-11b-
 hydroxy-3,20-
 dioxopregna-
 1,4-dien-21-al,
 Budesonide  BP  b) imp A  b) 11b,16a,17,
 21-tetra-
 hydroxypregna
 -1,4-diene-3,
 20-dione,
 Budesonide  BP  c) imp F  c) 16a,17-[1-
 methylethyli-
 denebis(oxy)]
 -11b,21-dihydr-
 oxypregna-1,
 4-diene-3,20-
 dione,
 Budesonide  INH  d) Pre-
 dniso-
 lone
 d) 11b,17,21-
 tetrahydrox-
 ypregna-1,
 4-diene-3,20-
 dione
 Budesonide  INH    e) Acetaldehyde
 Capace-
 tabine
 INH    a) 2’3’-dioacetyl-
 5’deoxy-5 fluor-
 ocytidine
 Capace-
 tabine
 INH    b) 4’-bromom-
 ethyl-5’-deoxy-
 5 fluoro-N-[(pen-
 tyloxy)carboxyl]
 cytidine
 Capace-
 tabine
 INH    c) 2’3’-diocetyl
 -5’-deoxy-5
 fluoro N-[(pent-
 yloxy)carbonyl]
 cytidine
 Capace-
 tabine
 INH    d) 5'-deoxy-5-
 fluorocytidine
 Captopril  BP  Imp A  (2S,2¢S)-1,1¢-
 [disulphaned-
 iylbis[(2S)-2-
 methyl-1-oxop-
 ropane-3,
 1-diyl]-bis
 [pyrro-lidine-
 2-carb-oxylic]
 acid(captopril
 -disulphide).
 Carboplatin  INH  Cisiod-  oplatin  
 Carboplatin  BP  Imp B  cyclobutane-1,
 1-dicarboxylic
 acid
 Carvedilol  BP  a) Imp B  a) 1,1¢-[[2-(2- 
 methoxyph-
 enoxy)ethyl]
 nitrilo]bis[3-
 (9H-carbazol
 -4-yloxy)
 propan-2-ol],
 Carvedilol  INH    b) Epoxy-
 Carbazole
 Carvedilol  BP  c) Imp A  c) 1-[[9-[2- 
 hydroxy-3-
 [[2-(2-metho-
 xyphenoxy)
 ethyl]amino]
 propyl]-9H-
 carbazol-4-yl]
 oxy]-3-[[2-
 (2-methox-
 yphenoxy)
 ethyl]amino]
 propan-2-ol,
 Carvedilol  INH    d) 1-propanol
 Carbazole
 Carvedilol  INH    e) C V Side
 Chain
 Carvedilol  INH    f) AEP  
 Compound
 Carvedilol  INH    g) Carvedilol
 polymorph
 Form-I
 Carvedilol  BP  h) Imp C  h) (2RS)-1-
 [benzyl[2-
 (2-methoxy-
 phenoxy)
 ethyl]amino]-3-
 (9H-carbazol
 -4-yloxy)
 propan-2-ol.
 Carvedilol  INH    i) 4-hydroxy
 Carbazole
 Celecoxib  INH    CX-I Compound
 Celecoxib  INH    HSA compound
 Ciclesonide  INH    a) Ciclesonides- 
 isomer(11P,
 16α)-16,17[[(S)-
 cyclohexy-
 lmethylene]
 bis(oxy)]-11-
 hydroxy-21-(2
methyl-1- 
 oxopropoxy)
 pregna-1,4-
 diene,3,20-
 dione
 Ciclesonide  INH    b) Propyla-
 nalogue
 Ciclesonide  INH    c) 16-α hydroxyl
 prednisolone
 Ciclesonide  INH    d) n- butyryl
 derivative
 Ciclesonide  INH    e) Isobytyryl
 derivative
 Ciclesonide  INH    f) Cyclohexyl
 derivative
 Ciclesonide  INH    g) Benzyl
 derivative
 Citalopram  INH    a) Citalopram
 Impurity `B’
 Citalopram  INH    b) Citalopram
 Impurity `D’
 Citalopram  INH    c) Citalopram
 Impurity `A’
 Citalopram  INH    d) Citalopram
 Impurity `C’
 Citalopram  INH    e) Des-bromo
 Citalopram
 Impurity
 Citalopram  INH    f) 5-chloro
 pthalide
 Clarithro- 
 mycin
 INH    a) Clarithr-
 omycin
 N-oxide
 Clarithro
 mycin
 EP  b) Imp D  b) N-Desmethyl
 clarithromycin
 Clarithro
 mycin
 INH    c) N-Desmethyl
 Erythromycin A
 Clarithro
 mycin
 EP  d) Imp H  d) N-Formyl
 Clarithromycin
 Clonazepam  BP  Imp A  a) 2-Amino2-‘-
 Chloro-
 5-Nitrobenzo-
 phenone
 Clonazepam  USP   Related
  comp-   ound 'B'
 a) 2-Amino2-‘-
 Chloro-
 5-Nitrobenzo-
 phenone
 Clopidogrel
 bisulphate
 INH    a) Racemate
  impurity of
 Clopidogrel
 Clopidogrel
 bisulphate
 INH    b) Acid Impurity
 of CLP
 Desloratidine  INH    a) N-formyl
 Desloratidine
 Desloratidine  INH    b) Loratidine
 Diazepam  USP  Related
 comp-
 ound B
 3-Amino-6-
 chloro-1-
 methyl-4-
 phenylcarbostyril
 Didanosine  INH  Hypox-
 anthine
 Imp A
 1,7-dihydro-
 6H-purin-6-
 one(hypox
 anthine)
 Didanosine  INH  Inosine-
 Imp B
 9-b-D-ribofur-
 anosyl-1,9-
 dihydro-6H-
 purin-6- 
 one(inosine)
 Didanosine  INH    2',3'-dideoxy-
 2',3'-didehydro
 inosine sodium
 Donepezil
 HCL
 INH    a) 4-[(5,6- 
 Dimethoxy-
 1-indanon
 -2-yl)methylene]
 pyridine
 Donepezil
 HCL
 INH    b) 1-Benzyl-
 4-[(5,6-
 dimethoxy-
 1-indanon-2-
 yl)methylene]
 pyridine bromide
 Donepezil
 HCL
 INH    c) 2-(4-Piperidinyl-
 methyl)-5,6- 
 dimethoxy-1-
 indanone
 Donepezil
 HCL
 INH    d) 1-Benzyl-4
 -[5,6-dimethoxy-
 1-oxoindan]methyl
 pyridine
 Duloxetine
 Hydrochloride
 INH  DLX -
 Racemic
 mixture
 (±)-N-Methyl-3-
 (1-napthalenyloxy)-
 3-(2-thienyl)
 propana-
 minoxalate
 Emtricifabine  INH    a) Emtricifabine
 Carboxylic acid
 impurity
 Emtricifabine  INH    b) Isomer
 impurity of
 Emtricifabine
 Emtricifabine  INH    c) 4-Amino,
 6fluoro 1-
 [(2R,5S)-2
  (hydroxy- 
 methyl)-
 1,3 oxathiolan-
 5-yl}-2(1H)
 pyrimidinone
 Emtricifabine  INH    d) Emtricitabine
 hydroxy
 Impurity
 Emtricifabine  INH    e) Emtricitabine
 sulfoxide
 Impurity
 Es-omeprazo
-le
 magnesium 
 dihydrate
 INH  N-oxide
 impurity
 5-Methoxy-2
 -[[(4-methoxy
 -3,5-dimethylp-
 yridin-2-yl)
 methyl]
 sulphinyl]-
 1H-benzimidazole- 
 1'-oxide
 Es-omeprazo
 -le
 magnesium
 dihydrate
 INH  Sulphon
 eimpurity
 5-Methoxy-
 2-[[(4-meth-
 oxy-3,
 5-dimethylp-
 yridine-2-yl)
 methyl]
 sulphonyl]-1H-
 benzimidazole
 Es- 
 omeprazo- 
 le
magnesium
 dihydrate
 INH  Desm-
 ethoxy
 impurity
 5-Methoxy-2
 -[[(3,5-dimethyl-
 pyridine-2-yl]
 methyl]
 sulphinyl]-
 1H-benzi-
 midazole
 Es-
omeprazo-
 le
 magnesium
 dihydrate
 INH  Sulphide
 impurity
 5-Methoxy-2
 -(4-methoxy
 -3,5-dimethylp-
 yridin-2-yl-
 methylthio)
 1H-benzi-
 midazole
 Esomeprazo-
 le
magnesium
 trihydrate
 INH  Omep-
 razole
 sulphone
 5-methoxy-2
 -[[(4-methoxy
 -3,5-dimethylpy-
 ridine-2-yl)
 methyl]
 sulphonyl]- 
 1H-benzimi-
 dazole
 Esomeprazo-
 le
magnesium
 trihydrate
 INH  Ome-
 prazole
 sulphide
 5-methoxy-2
 -(4-methoxy
 -3,5-dimethylp-
 yridin-2-yl-
 methylthio)
 1H-benzi
 midazole
 Esomeprazo-
 le
magnesium
 trihydrate
 INH  Omep-
 razole
 N-oxide
 5-methoxy-2-
 [[(4-methoxy-3,
 5-dimethyl-
 pyridin-2-yl)
 methyl]
 sulphinyl]-
 1H-benzimi-
 dazole-1'-
 oxide
 Estramustine  INH    a) Estramustine
 Estramustine  INH    b) 17-b
 phosphate
 estradiol
 Etoposide  BP  Imp D
 (lignan P)
 (5R,5aR,8aR,9S)
 -9-(b-D-glucopy-
 ranosyloxy)-
 5-(4-hydroxy-
 3,5-dimetho- 
 xyphenyl)
 -5,8,8a,9-
 tetrahy-
 droisobenzofuro
 [5,6-f][1,3]
 benzodioxol-6
 (5aH)-one
 (lignan P)
 Etoposide  INH    4’ de methyl
 epipodoph- 
 yllotoxin
 Etoposide  BP  Impurity
 C
 (5R,5aR,8aR,9S)
 -9-[[4,6-O-[(R)-
 ethylidene]-a-D-
 glucopyranosyl]
 oxy]-5- 
 (4-hydroxy-
 3, 5-dimethoxy-
 phenyl)-5,8,8a,9-
 tetrahydroisoben-
 zofuro[5,6-f]
 [1,3]benzo-
 dioxol-6(5aH)-
 one(a-etop-
 oside)
 Etoposide  BP  Impurity
 B
 (5R,5aS,8aR,9S)
 -9-[[4,6-O-[(R)-
 ethylidene]
 -b-D-glucopy-
 ranosyl]oxy]-5-
 (4-hydroxy- 
 3,5- dimethoxyp-
 henyl)-5,8,8a,9-
 tetrahydroiso-
 benzofuro
 [5,6-f][1,3]
 benzodioxol-
  6(5aH)-one
 (picroethylidene-
 lignan P;cis-
 etoposide)
 Etoposide  INH    4’-O-Carbob-
 enzyloxy
 4’-demethyl
  epipodop-
 hyllotoxin
 Etoposide  BP  impurity
 A
 (5R,5aR,8aR,9S)
 -5-[4-[[(benz-
 yloxy)carbonyl]
 oxy]-3,5-
 dimethoxy-
 phenyl]- 
 9-[[4,6-O-[(R)-
 ethylidene]-b-
 D-glucopyran-
 osyl]oxy]-5,8,
 8a,9-tetrahy-
 droisobenzofuro
 [5,6-f][1,3]
 benzodioxol- 
 6(5aH)-
 one(4¢-carbo-
 benzoyloxy-
 ethyliden-
 elignan P)
 Etoposide  BP  Imp I  (5R,5aR,8aR,9S)
 -9-[[4,6-O-[(R)-
 ethylidene]
 -b-D-glucopy-
 ranosyl]oxy]-5-
 (3,4,5-trimetho-
 xyphenyl)-5,
 8,8a,9-
 tetrahydrois-
 obenzofuro
 [5,6-f][1,3]
 benzodioxol
 -6(5aH)-one
 (4-O-methylethy-
 lidenelignan P)
 Famciclovir  INH    a) Famciclovir
 Impurity-1
 Famciclovir  INH    b) Famciclovir
 Impurity-2
 Famciclovir  INH    c) Des acetyl
 famciclovir
 Famotidine  BP  a) Imp C  a) 3-[[[2- 
 [(diamino-
 methylene)
 amino]thiazol
 -4-yl]methyl]
 sulphanyl]-N
 -sulphamoyl-
 propanamide,
 Famotidine  BP  b) Imp D  b) 3-[[[2-
 [(diamino-
 methylene)
 amino]thiazol
 -4-yl]methyl]
 sulphanyl]
 propanamide,
 Famotidine  BP  c) Imp F  c) 3-[[[2-
 [(diamino-
 methylene)
 amino]thia-
 zol-4-yl]
 methyl]
 sulphanyl]
 propanoic acid,
 Felodipine  BP  imp A  Ethylmethyl
 4- (2,3-dichlor-
 ophenyl)-2,6-
 dimethylpyridine-
 3,5-dicarboxylate
 Felodipine  BP  Imp B  Dimethyl 4-(2,3- 
 dichlorophenyl)
 -2,6-dimethyl
 -1,4-dihydro-
 pyridine-3,5- 
 dicarboxylate
 Felodipine  BP  Imp C  Diethyl 4-
 (2,3- 
dichlorophenyl)
-2,6-dimethyl
-1,4-dihydro-
pyridine
-3,5-dicarb-
oxylate
 Felodipine  USP  Related
 comp-
 ound A
Ethylmethyl 4-
(2,3-dichlo-
rophenyl)
-2,6-dimeth-
ylpyridine-3,
5-dicarboxylate
 Fenoteral
 Hydro
 bromide
 BP  a) Imp A  a) (1RS)-1-(3,5- 
 dihydoxyphenyl)
 -2-[[(1SR)-2
 -(4-hydroxy-
  phenyl)-
 1-methylethyl]
 amino]ethanol,
 Fluconazole  INH    a) Fluconazole
 Form-I
 Flutamide  BP  imp A  4-Nitro-3- 
 trifluorom-
 ethylaniline
 Flutamide  BP  Imp D  3-trifluoromethyl-
 aniline
 Flutamide  INH    3-trifluorom-
 ethylisobu-
 tyranilide
 Flutamide  INH    ortho flutamide
 Fluticasone
 propionate
 BP  a) Imp A  a)6a,9-difluoro-
 11b-hydroxy-
 16a-methyl-3-
 oxo-17-(propano-
 yloxy)androsta-1,
 4-diene-17b-
 carboxylic acid,
 Fluticasone
 propionate
 BP  b) Imp F  b) 6a,9-
 difluoro-
 17-[[(fluoro-
 methyl)
 sulphanyl]
 carbonyl]-
 16a-methyl-3,
 11-dioxoan-
 drosta-1,4-dien-
 17a-yl
 propanoate,
 Fluticasone
 propionate
 BP  c) Imp H  c) 17,17¢-
 (disulpha-
 nediyldica-
 rbonyl)bis(6a,9-
 difluoro-
 11b-hydroxy-
 16a-methyl-
 3-oxoand-
 rosta-1,
 4-dien-17
 a-yl) dipro-
 panoate,
 Fluticasone
 propionate
 INH    d) S-methyl
 Fluticasone
 propionate
 Fluticasone
 propionate
 INH    e) Fluticasone
 base
 Fluticasone
 propionate
 INH    f) Fluticasone
 acetate
 Fluticasone
 propionate
 INH    g) Dimmer
 impurity
 of Fluticasone
 Propionate
 Fluticasone
 propionate
 INH    h) Fluticasone
 Stage-V(iodo
 fluticasone)
 Fluticasone
 propionate
 INH    i) Fluticasone
 Stage-III(thio
 propionate)
 Formoteral  BP  a) Imp A  a) 1-(3-
 amino-4-
 hydroxyphenyl)-2- 
 [[2-(4-methoxyp-
 henyl)-1-methyl-
 ethyl}amino}
 ethanol
 Formoteral  BP  b) Imp C  b) N-[2-hydroxy-5
 [1-hydroxy-2-[[2-
 (4-metho- 
 xyphenyl- 1-
  methylethyl]
 amino]ethyl]
 phenyl]acetonide
 Gabapentin  INH    3,3-penta-
 methylene-
 5-butyrol-
 actam
 Gatifloxacin
 sesquihydrate
 INH    Desmethyl
 Gatifloxacin
 Gatifloxacin
 sesquihydrate
 INH    Gatifloxacin
 ester
 Gatifloxacin
 sesquihydrate
 INH    Gatifloxacin
 acid
 Granisetron
 Hydrochloride
 BP  imp A  2-methyl-
 N-[(1R,3r,
 5S)-9-methyl-
 9-azabicy-
 clo[3.3.1]
 non-3-yl]-
 2H-indazole-
 3-carboxamide
 Granisetron
 Hydrochloride
 BP  Imp B  N-[(1R,3r,5S)-
 9-methyl-9-
 azabicyclo
 [3.3.1]non-
 3-yl]-
 1H-indazole-
 3-carboxamide
 Granisetron
 Hydrochloride
 BP  Imp D  1-methyl-
 1H-indazole-
 3-carboxylic
 acid
 Granisetron
 Hydrochloride
 BP  Imp E  (1R,3r,5S)-
 9-methyl-
 9-azabicyclo
 [3.3.1]
 nonan-3-amine
 Imatinib
 mesylate
 INH    a) N-(2-Methyl-
 5-aminophenyl)-
 4-(3-Pyridyl)-
 2-Pyrimidine
 Amine.
 Imatinib
 mesylate
 INH    b) 4-[(4-
 Methyl-1-
 Piperazinyl)
 methyl]-N-
 [4-methyl-
 3-[4-(3-
 Pyridinyl)-
 2-Pyrimidinyl]
 chlorom-
 ethyl-amino]
 phenyl]
 Benzamide.
 Irinotican
 Hydrochloride
 Trihydrate
 INH    a) 7-ethyl
 camptothecin
 Irinotican
 Hydrochloride
 Trihydrate
 INH    b) 10-hy-
 droxy-7-
 ethylcampto-
 thecin
 Lamivudine  INH    a) 4-Amino-
 1-(2-(hydroxy-
 methyl)1,3 oxath-
 iolan-5-yl}-2(1H)
 pyrimidinone
 Lamivudine  BP  b) Imp A  b) Carboxylic
 acidimpurity
 of Lamivudine
 Lamivudine  INH    c) Salicylic acid
 Lamotrigine  INH    a) 2,3-dichloro-
 benzoylcyanide
 Lamotrigine  INH    b) 1-(1’cyano,
 1-amino-
  guanidine),
 2,3-dichlo-
 robenzene
 Lansoprazole  INH  Pharm-
 europa
 Imp B
 2-[[[3-methyl-4-
 (2,2,2-trifluoro-
 ethoxy)-2-
 pyridyl]-methyl]
 sulphonyl]-
 benzimidazole
 Lansoprazole  INH  Lansop-
 razole
 Sulphide
 2-[{[3-methyl-
 4-(2,2,2-trifluoro
 ethoxy)-2-
 pyridinyl]-
 methyl}
 thio]-1H-
 benzimid-
 azole
 Lansoprazole  INH  Lansop-
 razole
 N-oxide
 2-[[[3-methyl-4-
 (2,2,2-trifluoro-
 ethoxy)-2-
 pyridinyl]
 methyl]
 sulphinyl-1H- 
 benzimidazole-
 1-oxide
 Leflunomide  INH    a) N-
 (4-trifluoro-
 methylphenyl)-
 2-cyano-
 3-hydroxy
 crotonamide
 Leflunomide  INH    b) 2-Ethoxy-
 methylene
 acetoacetic
 acid-4-trilfuorom-
 ethylanilide
 Leflunomide  INH    c) 5-Methy-
 lisoxazole-
 4-carboxylic
 acid
 Leflunomide  INH    d) 3-Methyl-
 N-[4-trifluo-
 romethyl)
 phenyl]-4-
 isoxazole
 carboxamide
 Letrozole  INH    a) 4-fluor-
 obenzonitrile
 Letrozole  INH    b) (1H-1,2,
 4-triazol-1-
 yl-methylene)
 4-benzonitrile
 levofloxacine
 Hemihydrate
 INH    a) (-)-(S)-
 9-fluoro-2,
 3-dihydro-
 3-methyl-10-
 (1-piperazinyl)-
 7-oxi-7H-
 pyrido
 [1,2,3-del]-
 1,4-benzox-
 azine-6-
 carboxylic
 acid
 levofloxacine
 Hemihydrate
 INH    b) Chloromethyl
 esterimpurity
 levofloxacine
 Hemihydrate
 INH    c)N-Ethyl
 Levofloxacin
 impurity
 Losartan
 potassium
 INH    a) LSR-I
 compound
 Losartan
 potassium
 INH    b) TTBB
 Losartan
 potassium
 INH    c) BCFI
 Losartan
 potassium
 INH    d) Triphenyl
 methanol
 Mebendazole  BP  Imp A  a) (2-Amino-
 1H-benzoi-
 midazole-
 5-yl)phenyl-
 methanone
 Mitoxantrone
 Hydrochloride
 INH    Leuco 1,
 4,5,8-tetrahy-
 droxy
 anthra-
 quinone
 Mometasone
 furoate
 INH    a) Mometasone
 base
 Mometasone
 furoate
 INH    b) Mometasone
 difuroate
 Mometasone
 furoate
 INH    c) 21-hydroxy
 Mometasone
 Furoate
 Mometasone
 furoate
 INH    d) mometasone
 furoate
  epoxide
 Nevirapine  BP  a) Imp C  a) 4-methyl-
 11-propyl-
 5,11-dihydro-
 6H-dipyrido
 [3,2-b:2¢,3¢-e]
 [1,4]diazepin-6-
 one.
 Nevirapine  BP  b) Imp A  b) 11-ethyl
 -4-methyl-
 5,11-dihydro-
 6H-dipyrido
 [3,2-b:
 2¢,3¢-e]
 [1,4]diaz-
 epin-6-one,
 Nifedipine  BP  a) Imp A  a) dimethyl
 2,6-dimethyl-4-
 (2-nitrophenyl)
 pyridine-3,
 5-dicarbo-
 xylate
 (nitrophenylpy-
 ridine analogue),
 Nifedipine  BP  b) Imp B  b) dimethyl
 2,6-dimethyl-4-
 (2-nitroso-
 phenyl)
 pyridine-3,5-
 dicarb-
 oxylate
 (nitrosop-
 henylpyridine
 analogue),
 Nifedipine  USP  Nitrop-
 heny-
 lpyridine
 Analog
 Dimethyl
 4-(2-nitrop-
 henyl)-2,
 6-dimeth-
 ylpyridine-
 3,5-dicarbo-
 xylate
 Nifedipine  USP  Nitros-
 opheny-
 lpyridine
 Analog
 Dimethyl
 4-(2-nitro-
 sophenyl)-
 2,6-dime-
 thylpyridine-
 3,5-dicar-
 boxylate
 Norfloxacin  INH    a) N-5
 Compound
 Norfloxacin  INH    b) N-7
 Compound
 Norfloxacin  INH    c) Chloro
 analogue of
 Norfoxacin
 Ofloxacin  BP  imp A  9,10-difluoro-3-
 methyl-7-
 oxo-2,3-
 dihydro-
 7H-pyrido
 [1,2,3-de]-
 1,4-benzo
 xazine-
 6-carboxylic
 acid
 Ofloxacin  BP  Imp E  9-Fluoro-3-
 methyl-
 7-oxo-10-
 piperazin-
 1-yl)-2,3-
 dihydro-7H-
pyrido[1,2,3-
 de]-1,4- 
 benzoxazine-
 6-carboxylic
 acid
 Olanzapine  INH    a) Olanzapine
 ethyl
 analogue
 Olanzapine  INH    b) 4-hydroxy
 impurity of
 Olanzapine
 Olanzapine  INH    c) Olanzapine
 Form-II
 Olanzapine  INH    d) Olanzapine
 Form-I
 Olanzapine  INH    e) Des-N-Methyl
 Olanzapine
 Olanzapine  INH    f) ZP-I
 Compound
 Olanzapine  INH    g) ZP-II
 Compound
 Olanzapine  INH    h) ZP-III
 Compound
 Omeprazole  BP  imp A  5-methoxy-
 1H-benzimi-
 dazole-2-thiol.
 Omeprazole
 Magnesium
 BP  Imp B  2-[(RS)-
 [(3,5-dime-
 thylpyridin-
 2-yl)methyl]
 sulphinyl]
 -5-methoxy
 -1H-benzi-
 midazole.
 Omeprazole
 Sodium
 BP  Imp C  5-methoxy-
 2-[[(4-met-
 hoxy-3,5-
 dimethylp-
 yridin-2-yl)
 methyl]
 sulphanyl]
 1H- benz-
 imidazole.
 (ufiprazole)
 Omeprazole
 Sodium
 BP  Imp D  5-methoxy-
 2-[[(4-met-
 hoxy-3,5-
 dimethyl-
 pyridin-2-yl)
 methyl]
 sulphonyl]-
 1H-benzim-
 idazole
 (omeprazole
 sulphone)
 Omeprazole
 Sodium
 BP  Imp E  4-methoxy-
 2-[[(RS)-
 (5-methoxy-
 1H-benzim-
 idazol-2-yl)sulp-
 hinyl]methyl]-3,
 5-dimethy-
 lpyridine
 1-oxide
 Omeprazole
 Sodium
 INH  B5
 Hydro-
 chloride
 2-hydrox-
 ymethyl 3,
 5-dimethyl
 -4-methoxy
 pyridineh-
 ydrochloride
 Ondansetron
 hcl
 BP  a) Imp A  a) (3RS)-3-
 [(dimethy-
 lamino)
 methyl]-
 9-methyl-
 1,2,3,9-
 tetrahydro-
 4H-carbazol-
 4-one,
 Ondansetron
 hcl
 BP  b) Imp C  b) 9-
 methyl-
 1,2,3,9-
 tetrahydro-
 4H-carba-zol-
 4-one,
 Ondansetron
 hcl
 BP  c) Imp D  c) 9-methyl-
 3-methylene-
 1,2,3,9-tetrahy-
 dro-4H-carbazol-
 4-one,
 Ondansetron
 hcl
 BP  d) Imp G  d) (3RS)-
 3-[(1H-
 imidazol-
 1-yl)methyl]-
 9-methyl-
 1,2,3,9-
 tetrahydro-
 4H-carbazol-
 4-one(C-dem-
 ethylond-
 ansetron),
 Ondansetron
 hcl
 BP  e) Imp H  e) (3RS)-
 3-[(2-methyl-
 1H-imidazol-
 1-yl)methyl]-
 1,2,3,9-tetrahy-
 dro-4H-carbazol-
 4-one(N-deme-
 thylondansetron).
 Ondansetron
 hcl
 USP  Related
 comp-
 ound A
 3[(dimeth- 
 ylamino)
 methyl]-1,2,3,9-
 tetrahydro-
 9-methyl-4H-
 carbazol-4-one
 hydrochloride
 Ondansetron
 hcl
 USP  Related
 comp-
 ound D
 1,2,3,9-
 Tetrahydro-
 9-methyl-
 s3-methylene-
 4H-carbazol-
 4-one
 Ondansetron
 hcl
 USP  Related
 Comp-
 ound C
 1,2,3,9-
 Tetrahydro-
 9-methyl-
 4H-carbazol-
 4-one
 Ornidazole  INH    a) Ornid-
 azole
 epoxide
 Ornidazole  INH    b) Ornid-
 azolediol
 Oxaliplatin  BP  impurity
 A
 ethanedioic
 acid(oxalic acid)
 Pantoprazole
 sodium
 INH  Pharm-
 europa
 Imp A
 Pantoprazole
 sulphone is
 5(Difluoro
 methoxy)-
 2-[[(3,4-
 dimethoxy-
 2-pyridinyl)
 methyl]
 sulphonyl]-
 1H-benzimi-
 dazole
 Pantoprazole
 sodium
 INH  Pantop-
 razole
 sulphide

 5-(Difluo-
 romethoxy)-} 2-
 [[3,4-dimethoxy-
 2-pyridinyl]
 methyl]
 thio]-1H-benzimi-
 dazole

 Pantoprazole
 sodium
 sesquihydrate
 INH  Pantop-
 razole  sulpho
 ne-N- 
 oxide
 5-(Difluoro
 methoxy)-
 2-[[3,4-
 dimethoxy-
 2-pyridin
 -1-oxidenyl]
 methyl]
 sulphonyl]-
 1H-benzimi-
 dazole
 Paroxetine
 hydrochloride
 INH    a) PR-VI
 Compound
 Paroxetine
 hydrochloride
 INH    b) PR-VII
 Compound
 Potassium
 Clavulanate
 BP  a) Imp A  a) 2,2’-
 (pyrazine-
 2,5-diyl)
 diethanol
 Potassium
 Clavulanate
 BP  b) Imp B  b) 3-[3,6-
 bis(2-hyd-
 roxyethyl)
 pyrazine-
 2-yl}-propanoic
 acid
 Potassium
 Clavulanate
 BP  c) Imp C  c) 2,2’-(3-Ethyl
 pyrazine-2,5-
 diyl Diethanol
 Pramipexole  INH    a) Pramipexole
 impurity`E’
 Pramipexole  INH    b) PX-6
 Compound
 Pramipexole  INH    c) Impurity`D’
 of Pramipexole
 Pramipexole  INH    d) Impurity`F’
 of Pramipexole
 Pramipexole  INH    e) Impurity`A’
 of Pramipexole
 Pramipexole  INH    f) Pramipexole
 racemate
 compound
 Quetiapine
 fumarate
 INH    a) QTPP--IMP A
 Quetiapine
 fumarate
 INH    b) Qtp-04-imp B
 Rabeprazole
 sodium
 INH    a) 2-[[[4-(3-
 Methoxypropoxy)
 -3-methyl-2-
 pyridinyl]
 methyl]thio]-
 1H-
 benzimidazole
 Rabeprazole
 sodium
 INH    b) 2-[[[4-(3-
 Methoxy
 propoxy)-
 3-methyl-
 2-pyridinyl]
 methyl]
 sulfonyl]
 -1H-
 benzimidazole
 Rabeprazole
 sodium
 INH    c) 2-[[[4-
 (3-Methoxy)-3-
 methyl-2-pyrid-
 inyl]methyl]
 sulfonyl]-1H-
 benzimidazole
 Raloxifene
 HCL
 INH    a) 6-
 Methyl
 sulfonyloxy-2-
 [(4-methyl
 sulfonyloxy)
 phenyl-3[4(2-
 (piperidinyl)
 ethoxy]-benzoyl]
 benzothiophene
 hydrochloride
 Raloxifene
 HCL
 INH    b) 6-
 Hydroxy-
 2[4-hydroxy-
 phenyl]-
 3[4-hydroxy-
 benzoyl]
 benzothiophene
 Ramipril  BP  a) Imp E  a) (2S,-3aS,6aS)-
 1-[(S)-2-[[(S)-1-
 carboxy-3-phenyl-
 propyl]amino]
 propanoyl]octahy-
 drocyclo-penta[b]
 pyrrole-2-
 carboxylic
 acid(ramipril
 diacid),
 Ranitidine  USP  a) Relat
 ed com-
 pound c
 a) N-[2-[[[5-
 [(dimethylamino)
 methyl]-2-furanyl]
 methyl]sulphinyl]
 ethyl ]-N-methyl-
 2-Nitro1-1 Ethene
 diamine
 Ranitidine  USP  b) Relat
 ed com-
 pound A
 b) [5-[[2-aminoe-
 thyl)thio]
 methyl]-N-N-dim-
 ethyl-2-furan
 methan-amine,
 hemif-umarate
 salt]
 Ranitidine  BP

 a) imp B

 a) 2-[[[5-
 [(dimethylamino)
 methyl]furan-
 2-yl]methyl]
 sulphanyl]
 ethanamine,
 Ranitidine  BP  b) imp F  b) [5-[(dim-
 ethylamino)
 methyl]furan-2-
 yl]methanol,
 Ranitidine  BP  c) imp G  c) 3-(methy-
 lamino)-5,6-
 dihydro-2H-1,
 4-thiazin-2-one-
 oxime,
 Rifampicin  INH    a) 3-Formy-
 lrifamy-cin sv
 Rifampicin  INH    b) Isonicotinyl
 hydrazone
 of rifampicin
 and isonia-
 zide
 Risperidone  INH    a) 4-(2,4-
 Difluoro benzoyl
 hydroxylamino)
 piperidine
 Risperidone  INH    b) 6-Fluoro-
 3-(4-piperidinyl)
 -1,2-benzi-
 soxazole
 monohydroch-
 loride
 Risperidone  INH    c) 3-(2-
 chloroethyl)-2
 -methyl-4H-
 pyrido(1,2-a)
 pyrimidin-4-
 one
 Risperidone  INH    d) 6,7,8,9-
 tetrahydro-2
 -methyl-
 3-(2-chlo-
 roethyl)
 -4H-pyrido(1,2-a)
 pyrimidine
 -4-one hydro-
 chloride
 Risperidone  BP  e) Imp C  e)3-(2-(-4-
 (6-fluoro-1,2-
 benzisoxazol-
 3-yl)-1-piperid-
 inyl)ethyl)-
 2-methyl-4H-
 pyrido(1,2-a)
 pyrimidin-4-one
 Risperidone  INH  f) Rispe-
 ridone
 N-oxide
 
 Salbutamol
 sulfate
 BP  a) Imp C  a) (1RS)-2-
 [(1,1-dimethy-
 lethyl)amino]-
 1-(4-hyd-
 roxy-3-methyl-
 phenyl)ethanol,
 Salbutamol
 sulfate
 BP  b) Imp D  b) 5-[(1RS)-2-
 [(1,1-dimet- 
 hylethyl)amino]-
 1-hydroxyethyl]-2
 -hydroxybenzald-
 ehyde,
 Salbutamol
 sulfate
 BP  c) Imp I  c) (1RS)-2-[(1,1-
 dimethylethyl)
 amino]-1-[3-
 (hydroxymethyl)
 -4-benzyloxyp-
 henyl]ethanol.
 Salmeterol
 Xinofoate
 BP  a) Imp G  a) 1-[4-hydroxy-3
 -[[[2-hydroxy-
 2- [4-hydroxy-
 3-(hydroxymethyl)
 phenyl]ethyl]
 [6-(4-phenyl
 butoxy)hexyl]
 amino]methyl]
 phenyl]-2-[[6-
 (4-hen-ylbutoxy)
 hexyl]amino]
 ethanol.
 Salmeterol
 Xinofoate
 INH    b) 1-hydroxy-
 4[[2-hydroxy-
 5-[1-hydroxy-
 2-[[6-(-(4-Phenyl
 butoxy)hexyl]
 amino]ethyl]
 phenyl]methyl]-
 2-naphth-
 alenecarbo-
 xylicacid
 Salmeterol
 Xinofoate
 BP  c) Imp E  c) 1-[4-hyd-
 roxy-3-(hydro-
 xymethyl)phenyl]-
 2-[[6-(1-methyl-
 3-phenylpropoxy)
 hexyl]amino]
 ethanol,
 Selegiline
 Hydrochloride
 BP  Imp A  (2RS)-N-methyl-
 1-pheny-lpropan
 -2-amine[(RS)-
 metamphetamine]
 Sertraline
 hydrochloride
 INH    a) IST-01
 Compound
 Sertraline
 hydrochloride
 INH    b) 3,4deschloro
 Sertraline
 Sertraline
 hydrochloride
 INH    c) Sertraline
 base
 Sertraline
 hydrochloride
 INH    d) Cis(1R, 4R)
 Sertraline
 HCl
 Sertraline
 hydrochloride
 INH    e) NS-II
 Compound
 Sertraline
 hydrochloride
 INH    f) Trans
 isomer
 of NS-III
 Compound
 Sertraline
 hydrochloride
 INH    g) NS-III
 Compound
 (Racemic-
 sertraline)
 Sibutramine  INH    a) SM-III
 fumarate salt
 Sibutramine  INH    b) SM amide
 impurity
 Sibutramine  INH    c) Des-chloro
 Sibutramine
 Sildenafil  INH    a) Des methyl
 impurity of
 Sildenafil[3-[2-
 (dimethylamino)
 ethyl]-1-(hydro-
 xymethyl)-1H
 indol-5-yl]
 N-methyl
 methanesulpho-
 namide
 Stavudine  BP  a) Imp A  a)5-methylpy-
 rimidine-2,4
 (1H,3H)-dione
 (thymine)
 Stavudine  INH    b) 2’,3’-dideh-
 ydro,5’-O-
 Benzoyl,5-methyl
 uridine
 Sumatritan
 succinate
 USP  Imp
 Related  comp-
 ound 'C
 ([3-[2-
 (dimethylamino)
 ethyl]-1-(hydro-
 xy-methyl-
 1H-indol-
 5-yl]-N-methyl
 metha-nesulfo-
 namide succinate
 salt)
Tamsulosin
hydrochlo-
ride
 INH    a) (R)-5-{2-N,N
 bis[[2-(2-ethoxy
 phenoxy)
 ethyl]-amino]
 propyl}-2-
 methoxy
 benzene
 sulphonamide
Tamsulosin
hydrochlo-
ride
 INH    b) 2-methoxy-
 5-[2-(1,methyl
 benzyl-amino)
 propyl]benzene
 sulphonamide
Tamsulosin
hydrochlo-
ride
 INH    c) (S)-5-{2-[[2-
 (2-ethoxy-
 phenoxy)
 ethyl)amino]
 propyl}2-methoxy
 benzenesulphona-
 mide
Tamsulosin
hydrochlo-
ride
 INH    d) 2-bromoethyl-
 2-ethoxyphenyl
 ether
Tegaserod
Maleate
 INH  

 a) 5-Methoxy
 1H– Indole
 3-carbaldehyde

Tegaserod
Maleate
 INH    b) N-aminon-
 pentyl Guanidine
Terbinafine
hydrochlo-
ride
 INH  

 a) Terbinafine-Z-
 isomer N-[(2E)-
 6,6-dimethyl-
 2-hepten-4ynyl]
 N-methyl-1-
 naphth-
 alene-metha- 
 namine

Terbinafine
hydrochlo-
ride
 INH    b) Dimmer
 impurity
 of terbinafine
Tibolone  INH    a) α-Tibolone
 7α-methyl-17 α-
 ethynyl-17β
 hydroxy estr-
 5(10)-
 en-3-one
 Topiramate  INH    a) 2,3:4,5-bis-
 O-(1-methyl-
 ethylidene)-
 beta D
 fructopyranose
 Topiramate  INH    b) 2,3:4,5-bis-
 O-(1-methylethyli-
 dene)-beta-D-
 fructopyranose
 sulphamoyl
 azide
 Topotecan
 Hydrochloride
 INH    a) Campt-
 othecin
 Topotecan
 Hydrochloride
 INH    b) 10-Hydroxy
 camptothecin
 Torsemide  USP  Related
 comp-
 ound A
 (4[(3-methyl
 phenyl)amino]-
 3-pyridine sulpho-
 namide)
 Trimetazi-
dine dihydro-
chloride
 BP  a) Imp A  a) 1-(3,4,5-
 trimeth-
  oxybenzyl)
  piperazine,
 Trimetazidine  dihydrochlori-
 de
 BP  b) Imp C  b) 2,3,4
 trimethoxy
 benzaldehyde
 Trimetazidine
 dihydrochlori-
 de
 BP  c) Imp F  c) 2,4,6 
 trimethoxy
 TMZ impurity
 Trimetazidine
 dihydrochlori-
 de
 BP  d) Imp D  d) 2,3,4trimet-
 hoxyphenyl
 methanol
 Trimetazidine  dihydrochlori-
 de
 BP  e) Imp B  e) 1,4-bis(2,3,4-
 trimethoxybe-
 nzyl)pipera-
 zine,
 Trimetazidine  dihydrochlori-
 de
 BP  f) Imp E  f) 1-(2,4,5-
 trimeth-
 oxybenzyl)
 piperazine,
 Venlafaxine  hydrochloride  BP  a) Imp G  a) (2RS)-2-
 cyclohexyl-
 2-(4-methoxy-
 phenyl)-N,N-
 dimethyeth-
 anamine.
 Venlafaxine  hydrochloride  BP  b) Imp D  b) 1-[(1RS)-1-(4- 
 methoxyphenyl)-
 2-(methylamino)
 ethyl]cyclohe-
 xanol,
 Vincristine  sulphate  INH  Desfo-
 rmyl
 vincr-
 istine
 
 Zidovudine  BP  Imp D  Triphenyl
 methanol
 Zidovudine  BP  Imp C  5-methyl
 pyrimidine-
 2,4(1H,3H)-dione
 (thymine)

 If required impurity is not listed above,

 Please provide detail in additional comments area
 of the enquiry / order form.